If you had a 98 Sierra with 163,000 miles on it would you drive it from St. Louis mo to central Florida for vacation? Keep I. Mind I've owned this truck for 16 years..
Since you've owned it for so long, you're best able to make that decision.
I have a 98 Olds. I regularly drive from the upper midwest down to southern Indiana. The Olds has 184,500 miles.
Sure, you know it's mechanically sound, good tires. We took our old Plymouth with 250000 miles on it to Florida and back with no problems. But, That was a long time ago.