After doing some research, it seems U.S.-Iran relations are sour because of actions started by the U.S. Do you think we could ever have relations with Iran again, or is it too toxic? Also, any ideas how we could make it better?
Evidently, American culture is very popular among the younger generations in Iran. When the older hard liners die off, there will be opportunities for reconciliation.
One of the U.S's long time historical allies, and a great cultural influence. The flux of history will bend us and the Persian people back together.
Although not necessarily under the Ayatollahs regime
Whatever the case - yes we should have relations with them. We have relations with Germany, Japan, South Korea, England, Vietnam, and Mexico to name a few of the folks we had a war with.
Also China and Russia to name a few we have had other difficulties with. Also, we are striving to have better relations with North Korea and Cuba.
You could make a compelling case that it is the US's fault, but there's two sides to every coin.
There is very little we can do at the moment. Our interests and desires in the Middle East and the world at large are diametrically opposed. Our only hope is regime change or liberalization within the Iranian government, but the latter is unlikely.
It's never too late. How about forgive and forget but we have to go first.